Can the Damaged Brain Repair Itself?

Dr. Chandran is currently serving as the Director of Centre for Clinical Brain Sciences at the Euan MacDonald Centre and Anne Rowling Regenerative Neurology Clinic at the University of Edinburgh. 35 million people worldwide suffer from degenerative neurological disorders costing an average of 700 billion dollars annually, yet there is still not a recognized effective…

Self-assembling Peptide Scaffolds For Regenerative Medicine

John B. Matson, Samuel I. Stupp Bio-materials made from small peptide chains are ideal for creating scaffolds for tissue regeneration. Small peptides can assemble into spheres, cylinders, tubes, and many other useful scaffolding structures. Classes of Filamentous Supra-molecular Scaffolds Peptide amphiphiles are short chain peptides with a hydrophobic tail attached to a lipid chain capable of self…

Human Skeletal Stem Cell Found

  C.K.F. Chan et al., “Identification of the human skeletal stem cell,” Cell, doi:10.1016/ j.cell.2018.07.029, 2018.  Skeletal stem cells in humans, the bone marrow support cells, have been discovered. Researchers determined that these stem cells are self replicating and multipotent. Nonhematopoietic cells were taken from a human fetal femur and separated from blood precursors. The non…

A Bioengineered Factory for T-cells

Harvard University John A. Paulson School of Engineering and Applied Sciences Bone marrow transplants utilizing hematopoietic stem cells are currently being used as an effective treatment to combat life threatening cancers and infections. A transfusion of blood stem cells from a matched donor is injected into the patient to “reset the blood and immune system.”…

Regenerative Medicine: Current Therapies and Future Directions

Angela S. Mao, David J. Mooney Regenerative medicine is a medical practice focused on repairing tissue damage, replacing tissue and organs, and helping diminish the effects of congenital disorders. A major complication in organ transplantation, immune rejection, may be avoided entirely with the implementation of certain regenerative techniques for repairing damaged tissue. There are numerous…

Introduction to Stem Cell Therapy

Jesse K. Biehl, Brenda Russel Stem cells are a unique cell in their ability to not only replicate themselves but to specialize into specific cell types. There are two types of stem cells; pluripotent and multipotent. Pluripotent stem cells can specialize into any cell type within the body. Multipotent stem cells are more limited in…